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which NOX to target in vascular

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NOX isoforms in the development of abdominal …

Oxidative stress plays an important role in the formation of abdominal aortic aneurysm (AAA), and we have recently established a causal role of uncoupled eNOS in this severe human disease. We have also shown that activation of NADPH oxidase (NOX) lies upstream of uncoupled eNOS. Therefore
http://www.ncbi.nlm.nih.gov › … › Redox Biol › v.11; 2017 Apr

Endothelial NADPH oxidases: which NOX to target …

NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes implicated in the pathophysiology of vascular diseases such as hypertension and stroke. Endothelial cells express four NOX isoforms including the superoxide-generating enzymes NOX1, NOX2, and NOX5 and the hydrogen peroxide-generating enzyme NOX4. Studies on arteries from ...
https://www.readbyqxmd.com/read/25066192/endothelial-nadph...

Endothelial NADPH oxidases: which NOX to target …

Endothelial NADPH oxidases: which NOX to target in vascular disease? Drummond G.R., Sobey C.G. NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes implicated in the pathophysiology of vascular diseases such as hypertension and stroke.
https://www.uniprot.org/citations/25066192

Endothelial NADPH oxidases: which NOX to target in ...

Endothelial NADPH oxidases: which NOX to target in vascular disease? Grant R. Drummond1,2 and Christopher G. Sobey1,2 1Vascular Biology and Immunopharmacology Group, Department of Pharmacology, Monash University, Clayton, Victoria,
https://www.cell.com/trends/endocrinology-metabolism/pdf/S1043...

Endothelial NADPH oxidases: which NOX to target …

Endothelial NADPH oxidases: which NOX to target in vascular disease? Author: Grant R. Drummond,Christopher G. Sobey. Address: 1 Vascular Biology and Immunopharmacology Group, Department of Pharmacology, Monash University, Clayton, Victoria, Australia,2 Department of Surgery, Monash Medical Centre, Southern Clinical School, Monash ...
https://www.baikemy.com/periodical/view/subperiodical/...

Endothelial NADPH oxidases: Which NOX to target …

NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes implicated in the pathophysiology of vascular diseases such as hypertension and stroke.
https://www.researchgate.net/publication/264242078_Endothelial...

(PDF) Immune Mechanisms in Vascular Disease and …

NADPH oxidases (NOXs) are reactive oxygen species (ROS)-generating enzymes implicated in the pathophysiology of vascular diseases such as hypertension and stroke.
https://www.researchgate.net/publication/265473327_Immune...

Redox signaling, Nox5 and vascular remodeling in …

In hypertension, Nox-induced ROS production is increased, leading to perturbed redox signaling through oxidative modifications of vascular proteins. This influences mitogenic signaling and cell cycle regulation, leading to altered cell growth and vascular remodeling in hypertension.
http://www.ncbi.nlm.nih.gov › … › Lippincott Williams & Wilkins Open Access

Endothelial NADPH oxidases: which NOX to target …

Four NOX isoforms are expressed in the vascular wall, including NOX1 (in endothelial cells and vascular smooth-muscle cells, VSMCs), NOX2 (in endothelial cells, adventitial fibroblasts, and leukocytes such as monocytes, macrophages, and platelets), NOX4 (in endothelial cells, VSMCs, and adventitial fibroblasts), and NOX5 (in endothelial and VSMCs – not expressed in rodents).
https://www.sciencedirect.com/science/article/pii/S1043276014001234

Targeting Vascular NADPH Oxidase 1 Blocks Tumor ...

Targeting Vascular NADPH Oxidase 1 Blocks Tumor Angiogenesis through a PPARα Mediated Mechanism PLOS ONE , Feb 2011 Sarah Garrido-Urbani , Stephane Jemelin , Christine Deffert , Stéphanie Carnesecchi , Olivier Basset , Cédric Szyndralewiez , Freddy Heitz , Patrick Page , Xavier Montet , Liliane Michalik , et al.
http://paperity.org/p/61249982/targeting-vascular-nadph-oxidase-1-blocks...